Solid-Phase-Peptide-Synthesis Calculator
1. Resin Parameters
Resin Weight
g
Resin Loading
mmol/g
Total mmole:
0.050 mmol
2. Global Reagents
AA Default Eq
eq
Coupling Reagent
DIC
HATU
HBTU
PyBOP
PyMOP
eq
Additive
Oxyma Pure
HOBt
None
eq
Base
DIPEA
NMM
2,4,6-Collidine
TEA
eq
Solvent Conc.
M
3. Sequence Builder
Quick Import (N-term ā C-term)
Import
Enter sequence in standard NāC direction. System auto-assigns default protecting groups and builds from C-term.
ā OR ā
Manual Step Addition
Custom Name
Molecular Weight
g/mol
Add
At Step
Appends to N-term by default. Drag table rows to reorder.
SPPS Experiment Record
Project:
Operator:
Date:
Target Sequence:
Target MW:
Resin Weight:
g
Resin Loading:
mmol/g
Total mmole:
mmol
Total Reagents Summary
šØļø Print / PDF
Total Steps
0
Cou. R Total
0
Add. Total
0
Base Total
0
Total DMF
0 mL
Step-by-Step Synthesis Table
Clear Sequence
Target Seq (N ā C):
(Empty)
Deprotected Peptide Structure
Show Labels
Show PG
CPK Color
Reset View
Step
Amino Acid
AA Eq
AA Weight
Cou. R
Add.
Base
DMF
Action
Sequence is empty. Add amino acids from the Sequence Builder on the left.
* Synthesis proceeds from
Step 1 (C-term attached to resin)
towards N-term.